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Questions and answers for patients Questions and answers for medical professionals From sclerotherapy to T.R.A.P. |
Comparison between Sodium Salicylate in a buffered hydroglycerin vehicle and Cromic Glycerin"It is more sensible to prevent the formation of varices Some recent publications have indicated that chromic glycerin is superior to polydocanol in terms of both results and side-effects. Chromic glycerin is made up of glycerol and trivalent chromium. In susceptible subjects, this solution can trigger an allergic reaction to chromium. It should also be borne in mind that chromium salt contains a small amount of nickel and that, in subjects allergic to nickel (more than 50% of western populations), multiple injections can trigger a local or general reaction. Moreover, the literature contains reports of micro-haematuria following the injection of amounts of chromic glycerin greater than 10 ml. Our experience confirms that it is trivalent chromium which causes this kidney damage, as glycerol does not have this effect even if injected in high doses. The two photographs show a patient treated by a plastic surgeon colleague of ours in Genoa: the image on the left shows permanent hyperpigmentation caused by the injection of a chromic glycerin sclerosant a year earlier; on the right, the same patient is seen two weeks after the injection of a solution of 6% sodium salicylate in a hydroglycerin vehicle.
It therefore emerges that sodium salicylate in a hydroglycerin vehicle is the best tolerated solution and the one that causes the least hyperpigmentation (the rare cases that do occur are never definitive). Clearly, the hypersensitivity of patients to nickel and chromium, together with the untoward renal effects that can be caused by administering doses above 10 ml, means that solutions containing these metals cannot be used for T.R.A.P., which requires the injection of quantities ranging from a minimum of 12 ml to more 30 ml of solution. ReferencesZimmet, S. Visual disturbance following the use of scleremo in the treatment of leg telangiectasias. JDSO, volume 16, 1063, 1990 Brian C. Leach, MD, and Mitchel P. Goldman, MD: Comparative Trial Between Sodium Tetradecyl Sulfate and Glycerin in the Treatment of Telangiectatic Leg Veins, Dermatologic Surgery,Volume 29 Issue 6 Page 612 - June 2003 |
Three-dimensional Regenerative Phlebotherapy Fleboterapia tridimensional Regenerativa |
